Description

5-Methyl-2-(trifluoromethyl)benzonitrile is a high-value, fluorinated aromatic nitrile building block. This compound is prized for its unique chemical structure, which combines a nitrile group and a trifluoromethyl substituent on a methylated benzene ring, enabling precise molecular modifications. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for constructing complex molecules in drug discovery and development, particularly for candidates targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Serves as a critical precursor in the manufacture of advanced herbicides, fungicides, and insecticides, leveraging the stability and lipophilicity imparted by the trifluoromethyl group.
• Liquid Crystal & OLED Material Research: Used in the development of fluorinated organic electronic materials, where its structure contributes to desired dielectric and optical properties.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, cyano group transformations, and as a scaffold for introducing the trifluoromethyl moiety into more complex architectures.
• Chemical Research & Development: Essential for method development and exploring new reaction pathways in academic and industrial R&D laboratories.

Basic Information

Product Name	5-Methyl-2-(trifluoromethyl)benzonitrile
CAS No.	886502-61-0
Molecular Formula	C9H6F3N
Molecular Weight	185.15 g/mol
Synonyms	2-Cyano-4-methylbenzotrifluoride; 2-(Trifluoromethyl)-5-methylbenzonitrile; 5-Methyl-α,α,α-trifluoro-o-tolunitrile; 2-Methyl-5-(trifluoromethyl)benzonitrile; 2-Trifluoromethyl-5-methylbenzonitrile; Benzonitrile, 5-methyl-2-(trifluoromethyl)-; α,α,α-Trifluoro-5-methyl-2-tolunitrile
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for our fine chemical intermediates. Every batch of 5-Methyl-2-(trifluoromethyl)benzonitrile is analyzed using advanced techniques including HPLC, GC, and NMR to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment, and we support custom purity requirements for specific R&D or cGMP manufacturing applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.