Description

2,3-Difluoro-6-Methoxyphenylacetonitrile is a high-value fluorinated aromatic nitrile building block. This compound is critical for introducing the difluoromethoxy-phenyl moiety into complex molecular architectures, enabling the fine-tuning of physicochemical properties. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, particularly in medicinal chemistry for drug discovery programs.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders, oncology, and anti-infective therapies.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity, metabolic stability, and lipophilicity.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated compounds for electronic display applications, contributing to improved dielectric anisotropy and stability.
• Organic Electronics: Employed in the development of novel organic semiconductors and charge-transport materials for OLEDs and photovoltaic cells.
• Advanced Material Research: Acts as a versatile building block in academic and industrial R&D for creating complex fluorinated polymers and specialty chemicals with unique properties.

Basic Information

Product Name	2,3-Difluoro-6-Methoxyphenylacetonitrile
CAS No.	886501-94-6
Molecular Formula	C9H7F2NO
Molecular Weight	183.16 g/mol
Synonyms	2,3-Difluoro-6-methoxybenzyl cyanide; (2,3-Difluoro-6-methoxyphenyl)acetonitrile; 2-(2,3-Difluoro-6-methoxyphenyl)acetonitrile; 886501-94-6; α-Cyano-2,3-difluoro-6-methoxy toluene; 2,3-Difluoro-6-methoxybenzeneacetonitrile
EINECS	Contact for details

Quality Control

Our 2,3-Difluoro-6-Methoxyphenylacetonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates under cGMP and ISO guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.