Description

2,3-Difluoro-4-Methoxybenzylamine is a high-purity fluorinated benzylamine derivative, a key building block in advanced organic synthesis. Its value lies in its unique molecular structure, which incorporates fluorine atoms and a methoxy group to modulate the electronic and steric properties of target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders, oncology, and anti-infective agents.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a versatile building block for creating complex ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of specialty polymers, liquid crystals, and organic electronic materials due to its ability to fine-tune material properties.
• Fluorine Chemistry & SAR Studies: Integral for structure-activity relationship (SAR) studies in medicinal chemistry to explore the impact of fluorine substitution on potency and metabolic profile.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects and scale-up processes.

Basic Information

Product Name	2,3-Difluoro-4-Methoxybenzylamine
CAS No.	886500-75-0
Molecular Formula	C8H9F2NO
Molecular Weight	173.16 g/mol
Synonyms	(2,3-Difluoro-4-methoxyphenyl)methanamine; 1-(Aminomethyl)-2,3-difluoro-4-methoxybenzene; 2,3-Difluoro-4-methoxybenzenemethanamine; 4-Methoxy-2,3-difluorobenzylamine; 2,3-Difluoro-4-methoxybenzyl amine; α-Amino-2,3-difluoro-4-methoxytoluene; Benzenemethanamine, 2,3-difluoro-4-methoxy-; CAS 886500-75-0
EINECS	Contact for details

Quality Control

Our 2,3-Difluoro-4-Methoxybenzylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and consistency for critical R&D and production applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This amine derivative is hygroscopic (moisture-sensitive) and should be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from strong oxidizers and acids.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Standard Grade)
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.