Description

2-Methoxy-5-Trifluoromethoxy-Benzonitrile is a high-value, multi-functional aromatic nitrile building block distinguished by its unique trifluoromethoxy substituent. This compound is essential for advanced organic synthesis, offering a versatile scaffold for constructing complex molecules with tailored electronic and steric properties. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS disorders, inflammation, and oncology.
• Agrochemical Synthesis: Serves as a critical precursor in the design and synthesis of next-generation herbicides, fungicides, and insecticides, leveraging the stability imparted by the trifluoromethoxy group.
• Liquid Crystal & OLED Materials: Used in the research and production of advanced electronic materials, where its molecular structure contributes to desired dielectric anisotropy and luminescent properties.
• Organic Ligand & Catalyst Development: Employed in the synthesis of specialized ligands for catalysis and metal-organic frameworks (MOFs), facilitating novel chemical transformations.
• Polymer & Resin Modifier: Acts as a monomer or additive to introduce specific functionalities like enhanced solvent resistance or thermal stability into polymer chains.
• General Research & Custom Synthesis: A versatile building block for academic and industrial R&D across various fields of fine chemical and specialty chemical innovation.

Basic Information

Product Name	2-Methoxy-5-Trifluoromethoxy-Benzonitrile
CAS No.	886500-03-4
Molecular Formula	C9H6F3NO2
Molecular Weight	217.15 g/mol
Synonyms	5-(Trifluoromethoxy)-2-methoxybenzonitrile; 2-Methoxy-5-(trifluoromethoxy)benzonitrile; Benzonitrile, 2-methoxy-5-(trifluoromethoxy)-; 886500-03-4; 2-Methoxy-α,α,α-trifluoro-p-anisonitrile
EINECS	Contact for details

Quality Control

Our 2-Methoxy-5-Trifluoromethoxy-Benzonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates for GMP and non-GMP synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and strong oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.