Description

3-Fluoro-4-(Trifluoromethoxy)Benzonitrile is a high-value, multi-functional aromatic intermediate featuring a unique combination of fluorine and trifluoromethoxy substituents. This compound is critical for introducing lipophilicity, metabolic stability, and electronic properties into advanced molecular architectures. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients, including potential herbicides, insecticides, and pharmaceutical candidates.

Application

• Pharmaceutical Intermediate: A key building block for the research and synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology targets.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and insecticides, where the fluorine and trifluoromethoxy groups enhance biological activity and environmental stability.
• Liquid Crystal Materials: Serves as a precursor in the production of fluorinated liquid crystals for advanced display technologies.
• Organic Electronics: Employed in the synthesis of electron-deficient aromatic units for organic semiconductors and OLED materials.
• Chemical Research: A versatile reagent for introducing fluorinated aromatic motifs in medicinal chemistry and material science research programs.
• Custom Synthesis: Used as a starting material for the contract manufacturing of specialized fine chemicals and complex organic molecules.

Basic Information

Product Name	3-Fluoro-4-(Trifluoromethoxy)Benzonitrile
CAS No.	886498-94-8
Molecular Formula	C8H3F4NO
Molecular Weight	205.11 g/mol
Synonyms	4-Cyano-2-fluoro-1-(trifluoromethoxy)benzene; 2-Fluoro-α,α,α-trifluoro-p-tolunitrile 4-(Trifluoromethyl ether); 3-Fluoro-4-(trifluoromethoxy)benzonitrile; 4-(Trifluoromethoxy)-3-fluorobenzonitrile; Benzonitrile, 3-fluoro-4-(trifluoromethoxy)-; 886498-94-8
EINECS	Contact for details

Quality Control

We maintain rigorous quality control protocols for our fluorinated intermediates. Each batch of 3-Fluoro-4-(Trifluoromethoxy)Benzonitrile is analyzed using advanced techniques including HPLC, GC, and NMR to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. Our quality system is designed to meet the stringent requirements of cGMP and ISO standards for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.