Description

2,6-Difluoro-3-methoxyphenylacetonitrile is a versatile fluorinated aromatic nitrile building block of significant importance in advanced organic synthesis. Its molecular structure, featuring both fluorine and methoxy substituents, makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in the synthesis of kinase inhibitors, anti-cancer agents, and other biologically active heterocycles.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the difluoromethoxy motif can enhance metabolic stability and bioavailability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated liquid crystal compounds and electron-transport materials in organic light-emitting diodes (OLEDs) due to its influence on molecular polarity and packing.
• Functional Material Development: Employed in the synthesis of specialty polymers, ligands for catalysis, and advanced organic frameworks where fluorine substitution is desired.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	2,6-Difluoro-3-methoxyphenylacetonitrile
CAS No.	886498-69-7
Molecular Formula	C9H7F2NO
Molecular Weight	183.15 g/mol
Synonyms	2,6-Difluoro-3-methoxybenzyl cyanide; (2,6-Difluoro-3-methoxyphenyl)acetonitrile; 3-Methoxy-2,6-difluorobenzyl cyanide; 2,6-Difluoro-3-methoxybenzeneacetonitrile; α-Cyano-2,6-difluoro-3-methoxytoluene; 886498-69-7; DFMPA
EINECS	Contact for details

Quality Control

Our 2,6-Difluoro-3-methoxyphenylacetonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of research and industrial-scale applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee supply reliability and product traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.