Description

2,6-Difluoro-3-Methoxybenzonitrile is a high-purity fluorinated aromatic nitrile building block of significant importance in advanced organic synthesis. Its unique substitution pattern makes it a critical intermediate for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for researchers and manufacturers developing active ingredients, where its fluorine atoms and nitrile group enable precise modulation of biological activity and physicochemical properties.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel active pharmaceutical ingredients (APIs), especially in kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the difluoro-methoxy motif enhances efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Functional Material Research: Employed in the development of specialty polymers, ligands for catalysis, and advanced organic frameworks.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	2,6-Difluoro-3-Methoxybenzonitrile
CAS No.	886498-35-7
Molecular Formula	C8H5F2NO
Molecular Weight	169.13 g/mol
Synonyms	3-Methoxy-2,6-difluorobenzonitrile; 2,6-Difluoro-3-methoxybenzonitrile; 2,6-Difluoro-m-anisonitrile; Benzonitrile, 2,6-difluoro-3-methoxy-; 886498-35-7
EINECS	Contact for details

Quality Control

Our 2,6-Difluoro-3-Methoxybenzonitrile is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles, typically determined by advanced analytical techniques such as HPLC, GC, and NMR. We support development and commercial projects with customized specifications to meet specific application requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (typically 15-25°C). This material is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.