Description

2,3-Dichloro-6-Fluorophenylacetonitrile is a versatile halogenated aromatic nitrile building block of significant importance in advanced organic synthesis. Its molecular structure, featuring strategically placed chlorine and fluorine atoms adjacent to a reactive cyano group, makes it a critical intermediate for constructing complex molecules. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, including potential herbicides, fungicides, and pharmaceutical candidates.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex drug molecules, particularly those requiring halogenated aromatic scaffolds for bioactivity or metabolic stability.
• Agrochemical Synthesis: Serves as a foundational building block for developing new generations of herbicides, fungicides, and insecticides, leveraging the fluorine and chlorine substituents for enhanced efficacy.
• Material Science Research: Used in the development of specialty polymers, liquid crystals, and advanced organic electronic materials due to its rigid, halogenated aromatic core.
• Chemical Synthesis: Employed in organic chemistry research for cross-coupling reactions (e.g., Suzuki, Sonogashira) and cyano group transformations to create diverse libraries of compounds.
• Dye and Pigment Intermediate: Acts as a starting material for synthesizing specialized halogenated dyes and pigments with unique color fastness and properties.

Basic Information

Product Name	2,3-Dichloro-6-Fluorophenylacetonitrile
CAS No.	886497-54-7
Molecular Formula	C8H4Cl2FN
Molecular Weight	204.03 g/mol
Synonyms	(2,3-Dichloro-6-fluorophenyl)acetonitrile; 2,3-Dichloro-6-fluoro-benzeneacetonitrile; 2,3-Dichloro-6-fluorobenzyl cyanide; α-(2,3-Dichloro-6-fluorophenyl)acetonitrile; 886497-54-7; 2,3-Dichloro-6-fluorophenylacetonitrile; (2,3-Dichloro-6-fluorophenyl)ethanenitrile
EINECS	Contact for details

Quality Control

Our 2,3-Dichloro-6-Fluorophenylacetonitrile is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.