Description

3-Chloro-5-Fluoro-4-Methoxybenzonitrile is a high-purity, multi-functional aromatic nitrile building block of significant importance in advanced organic synthesis. Its unique substitution pattern, featuring chloro, fluoro, and methoxy groups, makes it a versatile intermediate for constructing complex molecular architectures. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, leveraging its halogenated aromatic structure.
• Liquid Crystal & OLED Materials: Serves as a precursor in the manufacture of specialty chemicals for electronic displays and organic light-emitting diodes.
• Functional Material Research: Employed in academic and industrial R&D for creating novel polymers, ligands, and advanced organic materials.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Item	Details
Product Name	3-Chloro-5-Fluoro-4-Methoxybenzonitrile
CAS No.	886497-30-9
Molecular Formula	C8H5ClFNO
Molecular Weight	185.58 g/mol
Synonyms	4-Methoxy-3-chloro-5-fluorobenzonitrile; 3-Chloro-5-fluoro-4-methoxybenzonitrile; Benzonitrile, 3-chloro-5-fluoro-4-methoxy-; 886497-30-9; 3-Chloro-5-fluoro-4-methoxy-benzonitrile
EINECS	Contact for details

Quality Control

Our 3-Chloro-5-Fluoro-4-Methoxybenzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality parameters. Our production adheres to cGMP guidelines where applicable, ensuring reliability for your most demanding synthesis projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.