Description

4-(1-Amino-2,2,2-Trifluoro-Ethyl)-Benzonitrile is a high-value, multi-functional chemical intermediate featuring a unique trifluoroethylamine-substituted benzonitrile core. This compound matters for its role as a critical building block in the synthesis of advanced molecules, particularly in the pharmaceutical and agrochemical sectors. Industries that require the precise introduction of fluorine atoms and amine functionality into complex structures, such as medicinal chemistry research and fine chemical manufacturing, are the primary users of this specialty chemical.

Application

• Pharmaceutical Intermediate: A key synthon for developing active pharmaceutical ingredients (APIs), especially in the research of kinase inhibitors, receptor modulators, and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the production of novel herbicides, fungicides, and insecticides where the trifluoromethyl group enhances biological activity and environmental stability.
• Material Science Precursor: Serves as a monomer or functionalization agent in the development of specialty polymers, liquid crystals, and advanced organic electronic materials.
• Fluorine Chemistry Research: An essential reagent for studying structure-activity relationships (SAR) and metabolic stability in medicinal chemistry due to its distinct fluorine pattern.
• Custom Synthesis & Contract Manufacturing: Employed by fine chemical companies for bespoke synthesis projects requiring this specific fluorinated aromatic amine.

Basic Information

Product Name	4-(1-Amino-2,2,2-Trifluoro-Ethyl)-Benzonitrile
CAS No.	886368-86-1
Molecular Formula	C9H7F3N2
Molecular Weight	200.16 g/mol
Synonyms	4-(1-Amino-2,2,2-trifluoroethyl)benzonitrile; 4-(2,2,2-Trifluoro-1-aminoethyl)benzonitrile; α-(Aminomethyl)-4-cyanobenzyltrifluoride; 4-Cyano-α-(trifluoromethyl)benzylamine; 886368-86-1; p-Cyanobenzylamine, α-(trifluoromethyl)-; Benzonitrile, 4-[(1-amino-2,2,2-trifluoroethyl)]-
EINECS	Contact for details

Quality Control

Our 4-(1-Amino-2,2,2-Trifluoro-Ethyl)-Benzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing identity, assay, and impurity profiles to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.