Description

(4-Fluoro-Phenyl)-(4-Oxo-Piperidin-1-Yl)-Acetic Acid CAS NO 886363-63-9 is a high-purity, synthetically derived organic compound featuring a piperidinone core linked to a fluorinated phenylacetic acid moiety. This molecular architecture makes it a critical advanced pharmaceutical intermediate (API) for the research and development of novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in drug discovery programs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and metabolic disorder targets.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for developing new drug candidates.
• Protease Inhibitor Synthesis: Serves as a precursor in the development of enzyme inhibitors due to its piperidinone scaffold.
• Chemical Reference Standard: Employed as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Bioconjugation & Probe Development: The carboxylic acid functional group allows for conjugation, useful in creating biochemical probes for diagnostic applications.

Basic Information

Product Name	(4-Fluoro-Phenyl)-(4-Oxo-Piperidin-1-Yl)-Acetic Acid
CAS No.	886363-63-9
Molecular Formula	C13H14FNO3
Molecular Weight	251.26 g/mol
Synonyms	1-[(4-Fluorophenyl)(carboxymethyl)]-4-piperidinone; 2-(4-Fluorophenyl)-2-(4-oxopiperidin-1-yl)acetic acid; 4-Fluoro-α-[(4-oxo-1-piperidinyl)carbonyl]benzenemethanol (tautomer); (4-Fluorophenyl)(4-oxopiperidin-1-yl)acetic acid; 886363-63-9; 1-(Carboxy(4-fluorophenyl)methyl)piperidin-4-one; 4-Oxo-1-piperidineacetic acid, α-(4-fluorophenyl)-
EINECS	Contact for details

Quality Control

Our (4-Fluoro-Phenyl)-(4-Oxo-Piperidin-1-Yl)-Acetic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and MS, to ensure it meets the stringent requirements for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.