Description

2-Fluoro-5-(3-Thienyl)Benzenecarbonitrile is a high-purity, multi-functional aromatic nitrile building block designed for advanced chemical synthesis. Its unique molecular architecture, featuring both a fluorinated benzene ring and a thiophene heterocycle, makes it a critical intermediate for developing novel materials and active pharmaceutical ingredients. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries seeking to incorporate specific fluorine and sulfur motifs into their target molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in kinase inhibitors and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, where the fluorine atom enhances biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a core building block for creating novel organic semiconductors, charge-transport materials, and emissive layers in display technologies.
• Polymer & Resin Modifier: Incorporated into specialty polymers to impart specific electronic properties, thermal stability, or chemical resistance.
• Chemical Research & Development: A versatile reagent for cross-coupling reactions (e.g., Suzuki, Stille) and cyano-group transformations in academic and industrial R&D labs.
• Dye & Pigment Precursor: Utilized in the synthesis of complex organic dyes and pigments with tailored optical properties.

Basic Information

Item	Detail
Product Name	2-Fluoro-5-(3-Thienyl)Benzenecarbonitrile
CAS No.	886361-71-3
Molecular Formula	C11H6FNS
Molecular Weight	203.23 g/mol
Synonyms	2-Fluoro-5-(thiophen-3-yl)benzonitrile; 3-(4-Cyano-2-fluorophenyl)thiophene; 5-(3-Thienyl)-2-fluorobenzonitrile; 2-Fluoro-5-(3-thienyl)benzonitrile; 886361-71-3; 2-Fluoro-5-(thiophene-3-yl)benzonitrile; Benzonitrile, 2-fluoro-5-(3-thienyl)-
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-5-(3-Thienyl)Benzenecarbonitrile is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We guarantee high purity and batch-to-batch consistency to meet the stringent requirements of advanced R&D and scale-up production. A detailed Certificate of Analysis (COA) confirming identity, purity (typically by HPLC), and impurity profile is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.