Description

2-Fluoro-4-(3-Thienyl)Benzenecarbonitrile is a high-purity, specialized organic building block featuring a unique fluorinated aromatic structure combined with a thiophene moiety. This compound is valued for its role as a critical intermediate in advanced organic synthesis, enabling the development of novel molecular architectures. It is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors for creating new active ingredients, as well as by material scientists exploring functional organic materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used in the synthesis of novel herbicides, fungicides, and insecticides, leveraging its fluorinated aromatic system for enhanced biological activity and stability.
• Material Science Research: Serves as a precursor for organic semiconductors, liquid crystals, and other functional materials where the thiophene-fluorobenzene combination imparts specific electronic or optical properties.
• Chemical Research & Development: Employed as a versatile building block in cross-coupling reactions (e.g., Suzuki, Stille) and other catalytic transformations to construct complex heterocyclic systems.
• Ligand and Catalyst Development: Useful for synthesizing specialized ligands for metal catalysis or as a core structure in catalyst design.

Basic Information

Product Name	2-Fluoro-4-(3-Thienyl)Benzenecarbonitrile
CAS No.	886361-69-9
Molecular Formula	C11H6FNS
Molecular Weight	203.23 g/mol
Synonyms	2-Fluoro-4-(thiophen-3-yl)benzonitrile; 4-(3-Thienyl)-2-fluorobenzonitrile; 3-(4-Cyano-3-fluorophenyl)thiophene; 2-Fluoro-4-(3-thienyl)benzonitrile; Benzonitrile, 2-fluoro-4-(3-thienyl)-; 886361-69-9
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-4-(3-Thienyl)Benzenecarbonitrile is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and scale-up applications. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles as determined by advanced chromatographic and spectroscopic methods.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.