Description

6-Amino-4-Fluoro-3-(1H)Indazole Carboxaldehyde is a high-purity, multi-functional heterocyclic building block of significant importance in advanced organic synthesis. Its core value lies in its unique molecular scaffold, which incorporates reactive aldehyde and amino groups on a fluorinated indazole core, enabling the construction of complex, biologically active molecules. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel drug candidates and active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors, particularly for oncology and anti-inflammatory drug discovery programs.
• Agrochemical Research: Used in the development of new herbicides and fungicides, leveraging the fluorine atom for enhanced bioactivity and metabolic stability.
• Chemical Biology Probe Synthesis: Serves as a versatile handle for creating fluorescent tags, affinity probes, and other tools for target identification and validation.
• Material Science: Potential building block for advanced organic electronic materials and metal-organic frameworks (MOFs) due to its rigid, planar structure and coordination sites.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds and libraries for high-throughput screening.

Basic Information

Product Name	6-Amino-4-Fluoro-3-(1H)Indazole Carboxaldehyde
CAS No.	885522-65-6
Molecular Formula	C8H6FN3O
Molecular Weight	179.15 g/mol
Synonyms	4-Fluoro-6-amino-1H-indazole-3-carboxaldehyde; 4-Fluoro-6-amino-1H-indazole-3-carbaldehyde; 6-Amino-4-fluoro-1H-indazole-3-carbaldehyde; 3-Formyl-6-amino-4-fluoro-1H-indazole; 885522-65-6; 6-Amino-4-fluoroindazole-3-carboxaldehyde; 4-Fluoro-6-aminoindazole-3-carboxaldehyde
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for this advanced intermediate. Every batch is characterized and tested to ensure identity, purity, and consistency, supporting critical R&D and scale-up activities. A comprehensive Certificate of Analysis (COA) detailing results from HPLC, NMR, and MS analysis is provided with each shipment to guarantee traceability and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.