Description

4-Fluoro-6-Methyl-3-(1H)Indazole Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate with a distinct indazole core structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in oncology and targeted therapy research. It is essential for medicinal chemistry R&D teams and fine chemical manufacturers engaged in developing next-generation small molecule drugs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel kinase inhibitors and other targeted cancer therapeutics.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Biochemical Tool Compound: Used in the development of probes and assay reagents for studying specific biological pathways and enzyme functions.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis to introduce the fluorinated indazole moiety into more complex molecular architectures.
• Contract Manufacturing (CMO): Supplied to contract development and manufacturing organizations (CDMOs) for cGMP production of clinical trial materials.

Basic Information

Product Name	4-Fluoro-6-Methyl-3-(1H)Indazole Carboxylic Acid
CAS No.	885522-19-0
Molecular Formula	C9H7FN2O2
Molecular Weight	194.16 g/mol
Synonyms	4-Fluoro-6-methyl-1H-indazole-3-carboxylic acid; 6-Methyl-4-fluoro-1H-indazole-3-carboxylic acid; 3-Carboxy-4-fluoro-6-methylindazole; 4-Fluoro-6-methylindazole-3-carboxylic acid; 885522-19-0; 4-Fluoro-6-methyl-1H-indazole-3-carboxylic acid; 4-Fluoro-6-methyl-3-indazolecarboxylic acid
EINECS	Contact for details

Quality Control

Our 4-Fluoro-6-Methyl-3-(1H)Indazole Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the stringent requirements for pharmaceutical R&D and development. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.