Description

4-Fluoro-3-Hydroxy-6-Nitroindazole is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its unique molecular scaffold, featuring fluorine, nitro, and hydroxyl substituents, makes it a critical intermediate for developing novel active pharmaceutical ingredients (APIs) and fine chemicals. This compound is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and material science sectors for lead optimization and the creation of complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors, anticancer agents, and other biologically active heterocyclic compounds.
• Agrochemical Research: Used in the development of new herbicides and pesticides, leveraging its nitroindazole core for bioactivity.
• Material Science: Serves as a building block for advanced organic electronic materials and functional dyes.
• Chemical Biology: Employed as a probe or linker in biochemical research due to its reactive functional groups.
• Academic & R&D: A valuable reagent for methodological studies in fluorination and nitro-group chemistry.
• Custom Synthesis: Used by contract research and manufacturing organizations (CROs/CMOs) for client-specific molecule development.

Basic Information

Product Name	4-Fluoro-3-Hydroxy-6-Nitroindazole
CAS No.	885520-04-7
Molecular Formula	C7H4FN3O3
Molecular Weight	197.12 g/mol
Synonyms	6-Nitro-4-fluoro-1H-indazol-3-ol; 4-Fluoro-6-nitro-1H-indazol-3-ol; 4-Fluoro-3-hydroxy-6-nitro-1H-indazole; 1H-Indazol-3-ol, 4-fluoro-6-nitro-; 885520-04-7; 4-Fluoro-6-nitroindazol-3-ol; 3-Hydroxy-4-fluoro-6-nitroindazole
EINECS	Contact for details

Quality Control

Our 4-Fluoro-3-Hydroxy-6-Nitroindazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation and to minimize degradation.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.