Description

2-Amino-5-Fluoro-4-Nitrobenzonitrile is a high-purity, multi-functional aromatic nitrile building block of significant importance in advanced organic synthesis. Its unique structure, featuring amino, fluoro, and nitro substituents, makes it a versatile intermediate for constructing complex heterocyclic systems and fine-tuning molecular properties. This compound is primarily sought by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and anti-infective applications.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and insecticides, where the fluorine atom enhances biological activity and metabolic stability.
• Dye and Pigment Manufacturing: Serves as a building block for creating specialized fluorinated dyes and pigments with unique color fastness and spectral properties.
• Material Science Research: Employed in the development of advanced organic materials, such as liquid crystals, organic semiconductors, and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized as a scaffold for creating fluorescent tags and molecular probes for diagnostic and bio-imaging applications.

Basic Information

Product Name	2-Amino-5-Fluoro-4-Nitrobenzonitrile
CAS No.	885269-10-3
Molecular Formula	C7H4FN3O2
Molecular Weight	181.13 g/mol
Synonyms	4-Nitro-2-amino-5-fluorobenzonitrile; 5-Fluoro-2-amino-4-nitrobenzonitrile; 2-Amino-5-fluoro-4-nitrobenzenecarbonitrile; Benzonitrile, 2-amino-5-fluoro-4-nitro-; 4-Cyano-2-fluoro-5-nitroaniline; 2-Fluoro-4-cyano-5-nitroaniline
EINECS	Contact for details

Quality Control

Our 2-Amino-5-Fluoro-4-Nitrobenzonitrile is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the stringent requirements of research and industrial synthesis. Certificates of Analysis (COA) detailing all specifications are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.