Description

2-Methyl-5-Fluorobenzoylacetonitrile is a versatile fluorinated organic intermediate characterized by its reactive nitrile and ketone functional groups. This compound is valued for its role in the synthesis of complex heterocyclic and pharmaceutical scaffolds, offering a strategic entry point for introducing fluorine atoms into target molecules. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for developing new active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated drug candidates, including kinase inhibitors and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the production of novel herbicides and pesticides where the fluorine moiety enhances biological activity and stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of organic semiconductors and fluorinated polymers with unique electronic or surface properties.
• Chemical Research & Development: A valuable reagent for method development and exploring new fluorination and cyclization reactions in academic and industrial labs.

Basic Information

Product Name	2-Methyl-5-Fluorobenzoylacetonitrile
CAS No.	884504-23-8
Molecular Formula	C10H8FNO
Molecular Weight	177.18 g/mol
Synonyms	5-Fluoro-2-methylbenzoylacetonitrile; 1-(5-Fluoro-2-methylphenyl)-3-oxobutanenitrile; 3-Oxo-3-(5-fluoro-2-methylphenyl)propanenitrile; 2-Methyl-5-fluorobenzoyl methyl cyanide; Acetonitrile, (5-fluoro-2-methylbenzoyl)-; (5-Fluoro-2-methylphenyl)-3-oxopropanenitrile
EINECS	Contact for details

Quality Control

Our 2-Methyl-5-Fluorobenzoylacetonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are provided with every shipment. We support compliance with cGMP, ISO, and other relevant regulatory frameworks for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and fluorides. The container must be kept tightly closed in a dry and inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.