Description

2,6-Difluoro-3-(2-Pyridnyl)-Benzonitrile is a high-value, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in the strategic combination of a pyridine ring, fluorine substituents, and a nitrile group, which enables precise molecular tuning for performance-driven applications. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel small-molecule drug candidates, particularly in kinase inhibitor and central nervous system (CNS) targeted therapies.
• Agrochemical Research: Serves as a critical scaffold for developing new-generation herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Ligand Synthesis: Used in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs) due to its chelating pyridyl moiety.
• Material Science: Employed in the research of organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, where its fluorine atoms improve stability and electron affinity.
• Fluorinated Building Block: Provides a versatile handle for further functionalization via the nitrile group and the fluorine atoms, enabling structure-activity relationship (SAR) studies.

Basic Information

Product Name	2,6-Difluoro-3-(2-Pyridnyl)-Benzonitrile
CAS No.	883106-18-1
Molecular Formula	C12H6F2N2
Molecular Weight	216.19 g/mol
Synonyms	3-(Pyridin-2-yl)-2,6-difluorobenzonitrile; 2,6-Difluoro-3-(pyridin-2-yl)benzonitrile; 2,6-Difluoro-3-(2-pyridinyl)benzonitrile; 2-Pyridine, 3-(2,6-difluorophenyl)carbonitrile derivative; Benzonitrile, 2,6-difluoro-3-(2-pyridinyl)-; 883106-18-1; 2,6-Difluoro-3-(2-pyridyl)benzonitrile
EINECS	Contact for details

Quality Control

Our 2,6-Difluoro-3-(2-Pyridnyl)-Benzonitrile is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and scale-up. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.