Description

5-Fluoro-2-Iodobenzonitrile is a high-purity, multi-functional halogenated aromatic building block essential for advanced organic synthesis. Its unique structure, featuring both fluorine and iodine substituents on a benzonitrile core, makes it a versatile intermediate for constructing complex molecules. This compound is particularly valuable for researchers and manufacturers in the pharmaceutical and agrochemical industries engaged in drug discovery, material science, and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds targeting central nervous system disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of halogenated aromatics.
• Material Science Research: Serves as a building block for creating specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: The iodine atom is an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to form biaryl structures.
• Fluorine Chemistry: The fluorine substituent is utilized to modulate the lipophilicity, metabolic stability, and bioavailability of target molecules.
• Chemical Reference Standard: Employed as an analytical standard in quality control and method development for related chemical processes.

Basic Information

Item	Detail
Product Name	5-Fluoro-2-Iodobenzonitrile
CAS No.	877868-92-3
Molecular Formula	C7H3FIN
Molecular Weight	262.01 g/mol
Synonyms	2-Iodo-5-fluorobenzonitrile; 5-Fluoro-2-iodobenzonitrile; 2-Cyano-4-fluoroiodobenzene; 4-Fluoro-2-iodobenzonitrile; Benzonitrile, 5-fluoro-2-iodo-; 877868-92-3
EINECS	Contact for details

Quality Control

Our 5-Fluoro-2-Iodobenzonitrile is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and industry best practices.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.