Description

2-Bromo-3,5-Difluoronitrobenzene is a high-value, multi-functional aromatic building block designed for advanced synthetic chemistry. Its unique halogenated and fluorinated structure makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors, where it serves as a versatile precursor for active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of fluorinated drug candidates.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated aromatic cores in electronic materials for displays and lighting.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and Buchwald-Hartwig amination reactions due to the reactive bromine substituent.
• Functional Dye & Pigment Synthesis: Employed in creating specialized fluorinated dyes and pigments with unique optical properties.
• Polymer & Resin Modifier: Used to introduce fluorine and nitro functional groups into polymer backbones to alter thermal and chemical resistance.

Basic Information

Product Name	2-Bromo-3,5-Difluoronitrobenzene
CAS No.	877161-74-5
Molecular Formula	C6H2BrF2NO2
Molecular Weight	237.99 g/mol
Synonyms	1-Bromo-2,4-difluoro-5-nitrobenzene; Benzene, 2-bromo-1,3-difluoro-5-nitro-; 2,4-Difluoro-5-nitro-1-bromobenzene; 5-Nitro-2,4-difluorobromobenzene; 2-Bromo-1,3-difluoro-5-nitrobenzene; 5-Bromo-2,4-difluoronitrobenzene
EINECS	Contact for details

Quality Control

Our 2-Bromo-3,5-Difluoronitrobenzene is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) for every shipment, detailing purity, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated synthesis pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flames. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant secondary packaging.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.