Description

Benzenepropanenitrile, 2-Fluoro- is a specialized fluorinated aromatic nitrile building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both a reactive cyano group and a fluorine substituent on the aromatic ring, makes it a versatile precursor for constructing complex molecules. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of fluorinated drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Serves as a building block for novel herbicides, fungicides, and insecticides where the fluorine atom enhances biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Used in the research and development of fluorinated components for electronic display and lighting technologies.
• Advanced Polymer Chemistry: Employed as a monomer or modifier to introduce fluorine and nitrile functionality into specialty polymers for enhanced chemical resistance.
• Chemical Synthesis Reagent: Functions as a versatile starting material for palladium-catalyzed cross-coupling reactions, nucleophilic aromatic substitution, and cyano group transformations.

Basic Information

Product Name	Benzenepropanenitrile, 2-Fluoro-
CAS No.	877149-83-2
Molecular Formula	C9H8FN
Molecular Weight	149.17 g/mol
Synonyms	2-Fluorobenzylacetonitrile; (2-Fluorophenyl)acetonitrile, 3-(2-Fluorophenyl)propanenitrile; 2-Fluoro-ω-cyanotoluene; 2-Fluorobenzeneacetonitrile; 3-(2-Fluorophenyl)propionitrile; β-(2-Fluorophenyl)propionitrile; 2-Fluoro-hydratroponitrile
EINECS	Contact for details

Quality Control

We maintain a strict quality management system to ensure batch-to-batch consistency and high purity for research and development applications. Our standard grade typically meets a purity specification of ≥97% (by HPLC), with detailed impurity profiling available. A comprehensive Certificate of Analysis (COA) is provided with each shipment, documenting identity, purity, and relevant physical data.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.