Description

Benzonitrile, 5-Bromo-3-Fluoro-2-Hydroxy- is a high-purity, multi-functional halogenated aromatic nitrile building block essential for advanced organic synthesis. This compound is valued for its unique molecular scaffold, which incorporates bromine, fluorine, and a phenolic hydroxyl group, enabling precise structural modifications in complex molecule construction. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of its halogen-substituted aromatic ring.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of advanced polymers, liquid crystals, and organic electronic materials due to its rigid, functionalized benzene core.
• Chemical Biology Probes: Utilized as a building block for fluorescent tags, photoaffinity labels, and other molecular probes in biochemical research.
• Custom Synthesis and Contract Manufacturing: A critical raw material for fine chemical manufacturers offering bespoke synthesis services to global clients.

Basic Information

Product Name	Benzonitrile, 5-Bromo-3-Fluoro-2-Hydroxy-
CAS No.	876918-40-0
Molecular Formula	C7H3BrFNO
Molecular Weight	216.01 g/mol
Synonyms	5-Bromo-3-fluoro-2-hydroxybenzonitrile; 2-Hydroxy-5-bromo-3-fluorobenzonitrile; 3-Fluoro-5-bromo-2-hydroxybenzonitrile; 2-Cyano-4-bromo-6-fluorophenol; 4-Bromo-6-fluoro-2-hydroxybenzonitrile; 6-Fluoro-4-bromo-2-hydroxybenzonitrile; 5-Bromo-3-fluorosalicylonitrile
EINECS	Contact for details

Quality Control

Every batch of Benzonitrile, 5-Bromo-3-Fluoro-2-Hydroxy- is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes data from HPLC, GC, NMR, and mass spectrometry. Our production adheres to cGMP guidelines where applicable, ensuring reliability for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.