Description

4-Amino-3-Bromo-5-Fluorobenzonitrile is a high-purity, multi-functional halogenated aniline derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring amino, bromo, fluoro, and nitrile substituents, makes it an exceptionally versatile intermediate for constructing complex molecular architectures. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, including potential drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules targeting central nervous system (CNS) disorders, oncology, and anti-infective therapies.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the halogen and nitrile groups contribute to biological activity and metabolic stability.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Proteomics: Employed as a versatile scaffold or labeling reagent for designing molecular probes, enzyme inhibitors, and bioconjugation tools.
• Dye & Pigment Intermediate: Acts as a starting material for synthesizing complex, halogenated dyes and pigments with specific color fastness and stability properties.

Basic Information

Product Name	4-Amino-3-Bromo-5-Fluorobenzonitrile
CAS No.	874880-58-7
Molecular Formula	C7H4BrFN2
Molecular Weight	215.02 g/mol
Synonyms	3-Bromo-5-fluoro-4-aminobenzonitrile; 4-Amino-3-bromo-5-fluorobenzene carbonitrile; 2-Bromo-6-cyano-3-fluoroaniline; Benzonitrile, 4-amino-3-bromo-5-fluoro-; 5-Fluoro-4-amino-3-bromobenzonitrile; 3-Bromo-5-fluoro-4-aminobenzonitrile; 4-Cyano-2-bromo-6-fluoroaniline
EINECS	Contact for details

Quality Control

Our 4-Amino-3-Bromo-5-Fluorobenzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and KF titration for moisture content, to ensure it meets the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.