Description

2-[4-(Trifluoromethyl)Phenoxy]Acetonitrile is a versatile fluorinated aromatic nitrile building block, offering a unique trifluoromethylphenoxy moiety for advanced chemical synthesis. This compound is critical for introducing specific steric and electronic properties into target molecules, enhancing their performance characteristics. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in the development of anti-inflammatory, antiviral, and CNS-active compounds.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the trifluoromethyl group improves biological activity and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated components used in electronic displays and organic light-emitting diodes.
• Polymer Modification: Employed to introduce fluorinated aromatic units into polymer backbones, enhancing material properties like chemical resistance and thermal stability.
• Organic Synthesis & Catalysis Research: A valuable reagent in academic and industrial research for constructing complex molecular architectures and exploring new catalytic cycles.
• Specialty Chemical Manufacturing: Intermediate for producing dyes, pigments, and other performance chemicals requiring specific fluorinated aromatic structures.

Basic Information

Product Name	2-[4-(Trifluoromethyl)Phenoxy]Acetonitrile
CAS No.	874804-02-1
Molecular Formula	C9H6F3NO
Molecular Weight	201.15 g/mol
Synonyms	4-(Trifluoromethyl)phenoxyacetonitrile; (4-Trifluoromethylphenoxy)acetonitrile; α-((4-(Trifluoromethyl)phenoxy)acetonitrile; Acetonitrile, 2-[4-(trifluoromethyl)phenoxy]-; 2-(4-Trifluoromethylphenoxy)acetonitrile; p-Trifluoromethylphenoxyacetonitrile; 4-CF3-Phenoxyacetonitrile
EINECS	Contact for details

Quality Control

Our 2-[4-(Trifluoromethyl)Phenoxy]Acetonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for use as a pharmaceutical intermediate.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. This material is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.