Description

2-Chloro-3-Fluorobenzonitrile is a versatile halogenated benzonitrile derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its bifunctional molecular structure, which allows for selective chemical transformations essential for creating complex target molecules. This intermediate is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules containing fluorinated aromatic systems.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the chloro-fluoro substitution pattern is beneficial.
• Liquid Crystal & OLED Material Development: Serves as a starting material for creating fluorinated liquid crystal compounds and organic light-emitting diode (OLED) materials.
• Functional Polymer Monomer: Employed in the development of specialty polymers with tailored properties such as chemical resistance and thermal stability.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to construct biaryl systems.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D labs exploring new synthetic methodologies and heterocyclic chemistry.

Basic Information

Product Name	2-Chloro-3-Fluorobenzonitrile
CAS No.	874781-08-5
Molecular Formula	C7H3ClFN
Molecular Weight	155.56 g/mol
Synonyms	2-Chloro-3-fluorobenzonitrile; 3-Fluoro-2-chlorobenzonitrile; 2-Chloro-3-fluorobenzene carbonitrile; Benzonitrile, 2-chloro-3-fluoro-; (2-Chloro-3-fluorophenyl)cyanide; 2-Chloro-3-fluoro-benzonitrile; 874781-08-5; 2-Cl-3-F-BN
EINECS	Contact for details

Quality Control

Our 2-Chloro-3-Fluorobenzonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for fine chemical intermediates. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee supply reliability and traceability for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque packaging or amber glass.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.