Description

1-(4-Methylphenyl)-3-(2,3,4-Trifluoroanilino)-1-Propanone is a high-purity fluorinated aromatic ketone derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its value lies in providing a versatile molecular scaffold for constructing complex pharmacologically active molecules, particularly those targeting central nervous system and anti-inflammatory pathways. This compound is essential for R&D and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality building blocks for drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those with fluorinated aromatic systems for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, where the trifluoromethylanilino moiety contributes to biological activity.
• Ligand & Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic semiconductors and photoactive materials for electronic applications.
• Custom Synthesis & Contract Manufacturing: A vital building block for custom synthesis houses serving the life sciences sector.
• Academic & Industrial R&D: Used in research laboratories for methodological studies and exploring new chemical reactions involving fluorinated compounds.

Basic Information

Product Name	1-(4-Methylphenyl)-3-(2,3,4-Trifluoroanilino)-1-Propanone
CAS No.	868255-64-5
Molecular Formula	C16H13F3N1O1
Molecular Weight	292.28 g/mol
Synonyms	3-[(2,3,4-Trifluorophenyl)amino]-1-(4-methylphenyl)propan-1-one; 1-Propanone, 1-(4-methylphenyl)-3-[(2,3,4-trifluorophenyl)amino]-; 1-(p-Tolyl)-3-((2,3,4-trifluorophenyl)amino)propan-1-one; 3-(2,3,4-Trifluoroanilino)-1-(4-methylphenyl)-1-propanone; 868255-64-5; 1-(4-Methylphenyl)-3-(2,3,4-trifluorophenylamino)propan-1-one
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is characterized using advanced analytical techniques to guarantee identity, purity, and consistency. We adhere to strict in-process controls and final release specifications. Certificates of Analysis (COA) detailing purity, impurity profile, and physical characteristics are available upon request and are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong alkalis and fluorides. The container must be kept tightly closed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.