Description

3,5-Dimethyl-4-Fluorobenzonitrile is a high-purity fluorinated aromatic nitrile building block of significant importance in advanced organic synthesis. Its molecular structure, featuring both fluorine and nitrile functional groups on a dimethyl-substituted benzene ring, makes it a versatile intermediate for constructing complex molecules. This compound is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical and agrochemical sectors for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Serves as a crucial building block for the synthesis of advanced herbicides, fungicides, and insecticides, leveraging the bioactivity imparted by the fluorine atom.
• Liquid Crystal Materials: Used in the synthesis of fluorinated liquid crystal compounds for display technologies, where the fluorine atom helps tune dielectric anisotropy and viscosity.
• Organic Electronic Materials: Acts as a precursor for electron-deficient units in the development of organic semiconductors, n-type materials, and non-fullerene acceptors for photovoltaic applications.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) due to the reactivity of the fluorine atom, enabling the construction of complex biaryl systems.
• Chemical Research: Employed in academic and industrial laboratories for methodological studies in fluorination chemistry and as a standard in analytical method development.

Basic Information

Product Name	3,5-Dimethyl-4-Fluorobenzonitrile
CAS No.	867367-02-0
Molecular Formula	C9H8FN
Molecular Weight	149.17 g/mol
Synonyms	4-Fluoro-3,5-dimethylbenzonitrile; 3,5-Dimethyl-4-fluorobenzonitrile; 4-Cyano-2,6-dimethylfluorobenzene; Benzonitrile, 4-fluoro-3,5-dimethyl-; 2,6-Dimethyl-4-fluorobenzonitrile
EINECS	Contact for details

Quality Control

Our 3,5-Dimethyl-4-Fluorobenzonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and reliability for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.