Description

(E)-1-(4-Benzylpiperazino)-4,4,5,5,5-Pentafluoro-1-Penten-3-One CAS NO 866144-14-1 is a high-purity, specialized fluorinated piperazine derivative designed for advanced chemical synthesis. This compound is valued for its unique molecular architecture, which incorporates a pentafluoropentenone moiety linked to a benzylpiperazine group, making it a versatile building block for creating novel molecules with targeted properties. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, due to the presence of the piperazine pharmacophore.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the introduction of fluorine atoms can enhance biological activity, stability, and metabolic resistance.
• Material Science: Acts as a monomer or cross-linking agent in the creation of specialty polymers and coatings with unique surface properties, such as oil and water repellency (fluorinated characteristics).
• Chemical Biology Probe: Employed in medicinal chemistry to create tool compounds for studying enzyme inhibition or receptor binding mechanisms.
• Fine Chemical Synthesis: A versatile scaffold for constructing complex organic molecules in academic and industrial research settings, enabling exploration of new chemical space.

Basic Information

Product Name	(E)-1-(4-Benzylpiperazino)-4,4,5,5,5-Pentafluoro-1-Penten-3-One
CAS No.	866144-14-1
Molecular Formula	C₁₆H₁₇F₅N₂O
Molecular Weight	348.32 g/mol
Synonyms	1-(4-Benzylpiperazino)-4,4,5,5,5-pentafluoro-1-penten-3-one; (E)-4,4,5,5,5-Pentafluoro-1-(4-benzylpiperazino)-1-penten-3-one; 866144-14-1; 4,4,5,5,5-Pentafluoro-1-(4-benzyl-1-piperazinyl)-1-penten-3-one; (E)-1-(4-Benzylpiperazino)-4,4,5,5,5-pentafluoropent-1-en-3-one; Benzylpiperazine pentafluoropentenone derivative; Pentafluoropentenone benzylpiperazine
EINECS	Contact for details

Quality Control

Our (E)-1-(4-Benzylpiperazino)-4,4,5,5,5-Pentafluoro-1-Penten-3-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP guidelines where applicable to support our clients in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.