Description

1-Bromo-4-(Difluoromethoxy)-2-Nitro-Benzene is a high-purity, multi-functional aromatic building block designed for advanced chemical synthesis. This compound is valued for its unique combination of halogen, nitro, and difluoromethoxy substituents, which enable precise molecular modifications. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and fungicides, leveraging its halogen and nitro groups for bioactivity.
• Material Science Research: Serves as a specialized monomer or additive in the development of advanced polymers and liquid crystals.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution to introduce complex functionalities.
• Fluorine Chemistry Studies: Acts as a model compound for studying the effects of the difluoromethoxy group on electronic properties and metabolic stability.

Basic Information

Product Name	1-Bromo-4-(Difluoromethoxy)-2-Nitro-Benzene
CAS No.	865886-84-6
Molecular Formula	C7H4BrF2NO3
Molecular Weight	267.02 g/mol
Synonyms	4-Bromo-1-(difluoromethoxy)-2-nitrobenzene; 2-Nitro-4-bromo-1-(difluoromethoxy)benzene; 1-Bromo-4-difluoromethoxy-2-nitrobenzene; Benzene, 1-bromo-4-(difluoromethoxy)-2-nitro-; 865886-84-6; 4-Bromo-2-nitro-1-(difluoromethoxy)benzene
EINECS	Contact for details

Quality Control

Our 1-Bromo-4-(Difluoromethoxy)-2-Nitro-Benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee batch-to-batch consistency and traceability for your R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.