Description

1,3-Difluoro-5-(3-Nitrophenyl)Benzene is a high-purity fluorinated aromatic building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both electron-withdrawing nitro and fluorine substituents, makes it a critical intermediate for constructing complex molecules with tailored electronic properties. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the preparation of novel herbicides and pesticides, where the difluoro and nitrophenyl groups contribute to biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Acts as a core building block for advanced electronic materials, including liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs), due to its influence on molecular polarity and mesomorphic properties.
• Polymer Chemistry: Incorporated into specialty polymers to enhance thermal stability, chemical resistance, and specific optical characteristics.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to create complex biaryl structures.
• Chemical Research & Development: A valuable reagent for academic and industrial research exploring new synthetic methodologies and novel compound libraries.

Basic Information

Item	Detail
Product Name	1,3-Difluoro-5-(3-Nitrophenyl)Benzene
CAS No.	865856-72-0
Molecular Formula	C12H7F2NO2
Molecular Weight	235.19 g/mol
Synonyms	3',5'-Difluoro-3-nitro-1,1'-biphenyl; 3-Nitro-3',5'-difluorobiphenyl; 5-(3-Nitrophenyl)-1,3-difluorobenzene; 1,3-Difluoro-5-(3-nitrophenyl)benzene; 3,5-Difluoro-3'-nitrobiphenyl; 3-(3,5-Difluorophenyl)nitrobenzene; 3-Nitro-3,5-difluorobiphenyl
EINECS	Contact for details

Quality Control

Our 1,3-Difluoro-5-(3-Nitrophenyl)Benzene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry best practices.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.