Description

3-Amino-4-Fluorobenzonitrile is a high-value aromatic nitrile and fluorinated aniline derivative, serving as a critical building block in advanced organic synthesis. Its bifunctional nature, featuring both an amino group and a fluorine atom ortho to a nitrile, makes it an exceptionally versatile intermediate for constructing complex molecular architectures. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science sectors for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly kinase inhibitors, anticancer agents, and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used to construct advanced herbicides, fungicides, and pesticides where the fluorine atom enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in catalytic processes and metal-organic frameworks (MOFs).
• Functional Material Research: Employed in the development of organic semiconductors, liquid crystals, and dyes due to its electron-withdrawing nitrile and modifiable amino group.
• Custom Chemical Synthesis: A versatile scaffold for contract research organizations (CROs) and fine chemical companies performing bespoke synthesis for clients.

Basic Information

Product Name	3-Amino-4-Fluorobenzonitrile
CAS No.	859855-53-1
Molecular Formula	C7H5FN2
Molecular Weight	136.13 g/mol
Synonyms	4-Fluoro-3-aminobenzonitrile; 3-Amino-4-fluorobenzene carbonitrile; 4-Fluoro-3-cyanobenzenamine; 3-Cyano-4-fluoroaniline; Benzonitrile, 3-amino-4-fluoro-; 4-Fluoro-m-aminobenzonitrile; 3-Amino-4-fluorophenyl cyanide
EINECS	Contact for details

Quality Control

Our 3-Amino-4-Fluorobenzonitrile is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality parameters. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.