Description

4-(2-Fluorophenyl)Tetrahydropyran-4-Carbonitrile, 97+% is a high-purity fluorinated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique tetrahydropyran core and fluorophenyl moiety impart desirable physicochemical properties. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate complex, fluorinated scaffolds into their target molecules.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides, leveraging the bioactivity-enhancing properties of the fluorine atom.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science: Potential monomer or additive for the synthesis of advanced polymers with specific optical or electronic properties.
• Chemical Biology Probes: Utilized in the design of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis houses offering bespoke chemical services to the life sciences sector.

Basic Information

Product Name	4-(2-Fluorophenyl)Tetrahydropyran-4-Carbonitrile, 97+%
CAS No.	859164-45-7
Molecular Formula	C₁₂H₁₂FNO
Molecular Weight	205.23 g/mol
Synonyms	4-(2-Fluorophenyl)tetrahydro-2H-pyran-4-carbonitrile; 4-Cyano-4-(2-fluorophenyl)tetrahydropyran; 2H-Pyran-4-carbonitrile, 4-(2-fluorophenyl)tetrahydro-; 4-(2-Fluorophenyl)-4-cyanotetrahydropyran; Tetrahydropyran-4-carbonitrile, 4-(2-fluorophenyl)-; 859164-45-7; 4-(2-Fluorophenyl)-4-cyanotetrahydro-2H-pyran
EINECS	Contact for details

Quality Control

Our 4-(2-Fluorophenyl)Tetrahydropyran-4-Carbonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure the 97+% minimum purity and identity are consistently met. Certificates of Analysis (COA) with detailed chromatographic data are provided for each lot, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed under an inert atmosphere to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.