Description

Ethyl cis-2-(4-Fluoro-2-Methylphenyl)Piperidine-4-Carboxylate is a high-purity, specialized piperidine derivative serving as a critical building block in advanced organic synthesis. Its molecular architecture, featuring a fluorinated aromatic ring and a carboxylate ester, makes it a valuable intermediate for constructing complex pharmacologically active molecules. This compound is primarily sought by research institutions and pharmaceutical development teams focused on creating new therapeutic agents, particularly in central nervous system (CNS) and metabolic disorder research.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for drug discovery programs.
• CNS Drug Development: Serves as a precursor in the synthesis of potential compounds targeting neurological receptors.
• Chemical Biology Probes: Utilized to create labeled or modified molecules for studying biological pathways and target engagement.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke synthesis projects.
• Academic Research: Used in university laboratories for methodological development and exploring new synthetic routes to heterocyclic compounds.

Basic Information

Product Name	Ethyl cis-2-(4-Fluoro-2-Methylphenyl)Piperidine-4-Carboxylate
CAS No.	857357-08-5
Molecular Formula	C15H20FNO2
Molecular Weight	265.33 g/mol
Synonyms	Ethyl cis-2-(4-Fluoro-2-methylphenyl)-4-piperidinecarboxylate; 4-Piperidinecarboxylic acid, 2-(4-fluoro-2-methylphenyl)-, ethyl ester, cis-; Ethyl 2-(4-fluoro-2-methylphenyl)-4-piperidinecarboxylate (cis-); cis-Ethyl 2-(4-fluoro-2-methylphenyl)piperidine-4-carboxylate; 857357-08-5; 4-Carbethoxy-2-(4-fluoro-2-methylphenyl)piperidine; Ethyl 2-(4-fluoro-o-tolyl)-4-piperidinecarboxylate
EINECS	Contact for details

Quality Control

Our Ethyl cis-2-(4-Fluoro-2-Methylphenyl)Piperidine-4-Carboxylate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the exacting standards required for pharmaceutical research and development. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% cis-isomer
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.