Description

4-Fluoro-3-Hydroxymethyl-Benzonitrile is a versatile and high-purity fluorinated benzonitrile derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both a hydroxymethyl and a fluorine substituent on the aromatic ring, makes it a valuable precursor for constructing complex molecules with tailored properties. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of fluorinated drug candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the fluorine atom enhances biological activity and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated aromatic compounds used in electronic displays and organic light-emitting diodes (OLEDs).
• Chemical Research & Development: A valuable reagent in academic and industrial R&D labs for exploring new fluorination reactions and creating novel chemical entities.
• Advanced Polymer Modification: Employed to introduce fluorinated aromatic units into polymer backbones, enhancing material properties like chemical resistance and thermal stability.

Basic Information

Product Name	4-Fluoro-3-Hydroxymethyl-Benzonitrile
CAS No.	856931-47-0
Molecular Formula	C8H6FNO
Molecular Weight	151.14 g/mol
Synonyms	4-Fluoro-3-(hydroxymethyl)benzonitrile; 3-(Hydroxymethyl)-4-fluorobenzonitrile; 4-Fluoro-3-hydroxymethylbenzonitrile; Benzonitrile, 4-fluoro-3-(hydroxymethyl)-; 856931-47-0; 4-Fluoro-3-(hydroxymethyl)phenyl cyanide
EINECS	Contact for details

Quality Control

Our 4-Fluoro-3-Hydroxymethyl-Benzonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with every shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most critical synthesis projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed to prevent absorption of moisture from the air. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.