Description

3-Bromomethyl-5-Fluoro-Benzonitrile is a versatile and high-purity aromatic building block essential for advanced organic synthesis. Its molecular structure, featuring both a reactive bromomethyl group and a fluorine substituent on a benzonitrile core, makes it a critical intermediate for constructing complex molecules. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, where the fluorine atom enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of advanced organic materials, such as liquid crystals and organic semiconductors, due to its aromatic and halogenated structure.
• Custom Chemical Synthesis: Utilized by contract research and manufacturing organizations (CROs/CMOs) for bespoke synthesis projects and scale-up processes.

Basic Information

Product Name	3-Bromomethyl-5-Fluoro-Benzonitrile
CAS No.	853368-35-1
Molecular Formula	C8H5BrFN
Molecular Weight	214.04 g/mol
Synonyms	5-Fluoro-3-(bromomethyl)benzonitrile; 3-(Bromomethyl)-5-fluorobenzonitrile; 5-Fluoro-3-bromomethylbenzonitrile; Benzonitrile, 3-(bromomethyl)-5-fluoro-; 853368-35-1; 3-Bromomethyl-5-fluorophenyl cyanide
EINECS	Contact for details

Quality Control

Every batch of 3-Bromomethyl-5-Fluoro-Benzonitrile is manufactured under strict quality management systems. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with industry standards and customer-specific requirements. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and away from moisture and direct light to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.