Description

4-(2-Fluorobenzyloxy)Benzonitrile is a high-purity fluorinated aromatic nitrile building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both a benzonitrile core and a fluorobenzyloxy substituent, makes it a versatile intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly for kinase inhibitors and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Serves as a building block for creating advanced herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Liquid Crystal Materials: Used in the synthesis of fluorinated liquid crystal compounds for display technologies, where the fluorine atom enhances stability and electro-optical properties.
• Organic Electronic Materials: Acts as a precursor for electron-deficient units in the development of organic semiconductors, OLEDs, and photovoltaic materials.
• Chemical Research & Development: Employed in academic and industrial R&D labs for methodology development, catalysis studies, and exploring new chemical spaces.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring specific fluorinated aromatic architectures.

Basic Information

Product Name	4-(2-Fluorobenzyloxy)Benzonitrile
CAS No.	852690-97-2
Molecular Formula	C14H10FNO
Molecular Weight	227.24 g/mol
Synonyms	4-[(2-Fluorophenyl)methoxy]benzonitrile; Benzonitrile, 4-[(2-fluorophenyl)methoxy]-; 2-Fluorobenzyl 4-cyanophenyl ether; p-Cyanophenyl 2-fluorobenzyl ether; 4-Cyanophenyl 2-fluorobenzyl ether; 4-(2-Fluorobenzyloxy)phenyl cyanide; 2-Fluoro-α-(4-cyanophenoxymethyl)benzene
EINECS	Contact for details

Quality Control

Our 4-(2-Fluorobenzyloxy)Benzonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming the product meets your specified requirements. Our quality commitment supports applications in cGMP and ISO-regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.