Description

2-Amino-3,5-Dibromo-6-Fluorobenzonitrile is a high-value, multi-halogenated aromatic building block of significant interest in advanced organic synthesis. Its unique structure, featuring amino, cyano, bromo, and fluoro substituents, makes it a versatile precursor for constructing complex molecular architectures. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors, receptor modulators, and other biologically active molecules.
• Agrochemical Synthesis: Serves as a crucial building block for creating advanced herbicides, fungicides, and insecticides, leveraging the bioactivity of halogenated anilines.
• Material Science Research: Used in the synthesis of specialized polymers, liquid crystals, and organic electronic materials due to its electron-withdrawing and steric properties.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and tags for studying biological processes and diagnostics.
• Cross-Coupling Reactions: The bromine atoms provide excellent handles for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to create more complex biaryl systems.
• Heterocyclic Chemistry: The amino and cyano groups can be utilized in cyclization reactions to construct nitrogen-containing heterocycles like benzimidazoles, quinazolines, and triazines.

Basic Information

Product Name	2-Amino-3,5-Dibromo-6-Fluorobenzonitrile
CAS No.	845878-91-3
Molecular Formula	C7H3Br2FN2
Molecular Weight	293.92 g/mol
Synonyms	6-Fluoro-2-amino-3,5-dibromobenzonitrile; 3,5-Dibromo-6-fluoro-2-aminobenzonitrile; 2-Amino-3,5-dibromo-6-fluorobenzonitrile; Benzonitrile, 2-amino-3,5-dibromo-6-fluoro-; 6-Fluoro-2-amino-3,5-dibromobenznitrile
EINECS	Contact for details

Quality Control

Our 2-Amino-3,5-Dibromo-6-Fluorobenzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We can support development and commercial projects requiring compliance with cGMP, ICH guidelines, and other relevant regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound may be light-sensitive and should be handled under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.