Description

3-Bromo-2-Fluorobenzonitrile is a versatile fluorinated aromatic nitrile building block of significant importance in advanced organic synthesis. Its molecular structure, featuring bromine and fluorine substituents on the benzonitrile core, makes it a critical intermediate for constructing complex molecules in pharmaceutical and agrochemical research. This compound is primarily utilized by R&D chemists and process development scientists in the life sciences sector for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Serves as a building block for developing new herbicides, fungicides, and insecticides with enhanced efficacy and environmental profiles.
• Liquid Crystal & OLED Material Synthesis: Used in the preparation of fluorinated aromatic components for electronic display materials and organic light-emitting diodes.
• Cross-Coupling Reactions: The bromine atom is an excellent handle for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl systems.
• Functional Material Development: Employed in creating advanced polymers, ligands for catalysis, and other specialty chemicals requiring halogenated aromatic nitriles.

Basic Information

Product Name	3-Bromo-2-Fluorobenzonitrile
CAS No.	840481-82-5
Molecular Formula	C7H3BrFN
Molecular Weight	200.01 g/mol
Synonyms	2-Fluoro-3-bromobenzonitrile; 3-Bromo-2-fluorobenzene carbonitrile; Benzonitrile, 3-bromo-2-fluoro-; 840481-82-5; 3-Br-2-F-C6H3-CN
EINECS	Contact for details

Quality Control

Our 3-Bromo-2-Fluorobenzonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide detailed Certificates of Analysis (COA) with every shipment, documenting purity, impurity profiles, and physical data. Our quality commitment aligns with cGMP principles for advanced intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.