Description

2,6-Difluoro-4-Morpholin-4-Ylbenzonitrile is a high-value, multi-functional aromatic nitrile building block featuring a morpholine substituent. This compound is critical for its role as a key intermediate in the synthesis of advanced pharmaceutical agents and agrochemicals, enabling the introduction of specific fluorine and nitrogen-containing pharmacophores. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the difluoro-morpholinobenzonitrile scaffold.
• Material Science Research: Serves as a precursor for organic electronic materials, such as ligands for OLEDs or components of advanced polymers.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and tags for studying biological systems and enzyme activity.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	2,6-Difluoro-4-Morpholin-4-Ylbenzonitrile
CAS No.	840481-30-3
Molecular Formula	C11H10F2N2O
Molecular Weight	224.21 g/mol
Synonyms	4-(2,6-Difluorophenyl)morpholine-4-carbonitrile; 2,6-Difluoro-4-morpholinobenzonitrile; Benzonitrile, 2,6-difluoro-4-morpholino-; 4-Morpholino-2,6-difluorobenzonitrile; 840481-30-3; 2,6-Difluoro-4-(morpholin-4-yl)benzonitrile
EINECS	Contact for details

Quality Control

Our 2,6-Difluoro-4-Morpholin-4-Ylbenzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed to minimize exposure to atmospheric moisture and light to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.