Description

4-(Difluoromethoxy)-3-Methoxyaniline is a specialized aromatic amine derivative featuring both difluoromethoxy and methoxy substituents. This compound is a high-value intermediate prized for its role in the synthesis of advanced molecules, particularly within the pharmaceutical and agrochemical sectors. It is primarily sought after by research institutions and industrial manufacturers developing novel active ingredients, where its unique fluorine-containing scaffold is critical for modulating biological activity and physicochemical properties.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of new drug candidates, particularly in areas like kinase inhibitors and central nervous system (CNS) agents.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the difluoromethoxy group can enhance metabolic stability and bioavailability.
• Liquid Crystal & Electronic Materials: Serves as a precursor for advanced materials used in display technologies and organic semiconductors.
• Organic Synthesis & Research: A versatile reagent for academic and industrial R&D in fluoroorganic chemistry, enabling the introduction of complex aniline motifs.
• Dye & Pigment Intermediate: Employed in the synthesis of specialized dyes and pigments requiring specific light-fastness and color properties.

Basic Information

Product Name	4-(Difluoromethoxy)-3-Methoxyaniline
CAS No.	832739-34-1
Molecular Formula	C8H9F2NO2
Molecular Weight	189.16 g/mol
Synonyms	3-Methoxy-4-(difluoromethoxy)aniline; 4-Amino-2-(difluoromethoxy)anisole; 1-Amino-4-(difluoromethoxy)-3-methoxybenzene; 4-(Difluoromethoxy)-3-methoxybenzenamine; 3-Methoxy-4-(difluoromethoxy)benzenamine; Benzenamine, 4-(difluoromethoxy)-3-methoxy-
EINECS	Contact for details

Quality Control

Our 4-(Difluoromethoxy)-3-Methoxyaniline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is easily oxidized and should be handled under an inert atmosphere for long-term storage. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Light yellow to brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.