Description

1-(3,4-Dimethoxy-Phenyl)-4,4-Difluorobutane-1,3-Dione is a high-purity difluorinated diketone building block of significant interest in advanced organic synthesis. Its unique structure, featuring both electron-donating methoxy groups and electron-withdrawing fluorine atoms, makes it a versatile precursor for creating complex heterocycles and functional materials. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients. Its reliable quality and consistent performance are critical for process development and scale-up activities.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in constructing fluorinated heterocyclic scaffolds with potential biological activity.
• Agrochemical Synthesis: Used in the development of advanced crop protection agents, where the introduction of fluorine atoms can enhance metabolic stability and bioactivity.
• Material Science Research: Serves as a building block for novel organic electronic materials, ligands for catalysis, and specialty polymers requiring specific fluorinated motifs.
• Chemical Research & Development: Employed in academic and industrial R&D labs for methodology development, exploring new reactions involving fluorinated 1,3-dicarbonyl compounds.
• Ligand and Catalyst Preparation: Useful for synthesizing chelating ligands or metal-organic frameworks (MOFs) due to its diketone functionality.

Basic Information

Product Name	1-(3,4-Dimethoxy-Phenyl)-4,4-Difluorobutane-1,3-Dione
CAS No.	832739-17-0
Molecular Formula	C₁₂H₁₂F₂O₄
Molecular Weight	258.22 g/mol
Synonyms	4,4-Difluoro-1-(3,4-dimethoxyphenyl)butane-1,3-dione; 3,4-Dimethoxyphenyl 4,4-difluorodiketone; 1-(3,4-Dimethoxyphenyl)-4,4-difluorobutane-1,3-dione; 4,4-Difluoro-1-(3,4-dimethoxyphenyl)-1,3-butanedione; DFDB; 832739-17-0; Difluorinated Dimethoxyphenyl Diketone
EINECS	Contact for details

Quality Control

Our 1-(3,4-Dimethoxy-Phenyl)-4,4-Difluorobutane-1,3-Dione is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity assessment and NMR for structural confirmation. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.