Description

3-(2-Fluoro-Phenyl)-Isoxazole-5-Carbaldehyde is a versatile fluorinated isoxazole derivative, a key heterocyclic building block prized for its unique reactivity. This compound is essential for the synthesis of complex molecules, particularly in the development of novel active pharmaceutical ingredients (APIs) and advanced agrochemicals. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing targeted molecular architectures.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and kinase inhibitors.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the isoxazole and fluorine motifs.
• Material Science: Serves as a building block for advanced organic materials, including liquid crystals, organic semiconductors, and functional polymers.
• Chemical Synthesis: The aldehyde group provides a versatile handle for further functionalization via condensation, reduction, or nucleophilic addition reactions, enabling library synthesis for high-throughput screening.
• Academic & Contract Research: A valuable reagent for methodological development and exploratory chemistry in university and CRO (Contract Research Organization) laboratories.

Basic Information

Item	Details
Product Name	3-(2-Fluoro-Phenyl)-Isoxazole-5-Carbaldehyde
CAS No.	808740-52-5
Molecular Formula	C10H6FNO2
Molecular Weight	191.16 g/mol
Synonyms	2-Fluoro-3-(isoxazol-5-yl)benzaldehyde; 5-Formyl-3-(2-fluorophenyl)isoxazole; 3-(2-Fluorophenyl)-1,2-oxazole-5-carboxaldehyde; 3-(o-Fluorophenyl)isoxazole-5-carbaldehyde; (2-Fluorophenyl)-5-isoxazolecarboxaldehyde; Isoxazole-5-carbaldehyde, 3-(2-fluorophenyl)-; 808740-52-5
EINECS	Contact for details

Quality Control

Every batch of 3-(2-Fluoro-Phenyl)-Isoxazole-5-Carbaldehyde is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and scale-up. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles by HPLC, NMR, and MS is supplied with each shipment to guarantee traceability and consistency for your critical synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive and easily oxidized; for long-term storage, consider keeping under an inert atmosphere (e.g., nitrogen or argon) to maintain optimal purity and stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.