Description

Cyanomorpholinodaunomycin is a synthetic derivative of the anthracycline antibiotic daunorubicin, modified with a cyanomorpholino group at the C-3' position of the sugar moiety. This structural modification is designed to enhance its pharmacological profile, potentially improving its efficacy and altering its metabolic pathway. It is primarily utilized in advanced pharmaceutical research and development, particularly in the field of oncology. This compound is of significant interest to researchers and developers focused on creating novel chemotherapeutic agents and studying drug resistance mechanisms.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the development of novel anthracycline-based anticancer drugs.
• Oncology Research: Used as a reference standard or active compound in biochemical and cellular assays to study mechanisms of action, cytotoxicity, and DNA intercalation.
• Drug Discovery Programs: Employed in structure-activity relationship (SAR) studies to optimize the potency and reduce the cardiotoxicity associated with anthracycline therapies.
• Biochemical Tool: Acts as a probe in molecular biology to investigate topoisomerase II inhibition and apoptosis pathways in cancer cells.
• Academic & Institutional Research: Utilized in universities and research institutes for fundamental studies in medicinal chemistry and experimental pharmacology.

Basic Information

Product Name	Cyanomorpholinodaunomycin
CAS No.	89164-74-9
Molecular Formula	C30H33N3O10
Molecular Weight	595.60 g/mol
Synonyms	3'-Deamino-3'-[2-(cyanomethyl)-4-morpholinyl]daunorubicin; 3'-(Cyanomorpholino)daunorubicin; 4'-O-Acetyl-3'-deamino-3'-(N-cyanomethyl-N-morpholino)daunorubicin; Daunorubicin, 3'-deamino-3'-[2-(cyanomethyl)-4-morpholinyl]-; Cyanomorpholino daunomycin; NSC 357704
EINECS	Contact for details

Quality Control

Our Cyanomorpholinodaunomycin is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support research and development with materials suitable for preclinical studies, ensuring reliable and reproducible results.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label or COA. For long-term storage, consider keeping the product in a freezer at -20°C under an inert atmosphere. The container should be kept in a dry, well-ventilated area.

Specification

Item	Specification
Appearance	Orange to red powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.