Description

Cytodex 3 is a microcarrier specifically designed for the large-scale culture of anchorage-dependent animal and human cells. This product is essential for enabling high-yield, reproducible cell growth in bioreactors, a critical step in the production of vaccines, monoclonal antibodies, and other biopharmaceuticals. It is primarily needed by biotechnology and pharmaceutical companies engaged in upstream bioprocessing, as well as academic and research institutions focused on cell biology and tissue engineering. Cytodex 3 CAS NO 88895-19-6 offers a consistent, collagen-coated surface optimized for cell attachment and proliferation.

Application

• Vaccine Production: Cultivation of cell lines (e.g., Vero, MRC-5) used as substrates for viral vaccine manufacturing.
• Monoclonal Antibody (mAb) Production: Scalable culture of hybridoma or recombinant mammalian cell lines (e.g., CHO, HEK293) for therapeutic antibody harvest.
• Cell Therapy & Regenerative Medicine: Expansion of stem cells, mesenchymal stromal cells (MSCs), and other therapeutic cell types.
• Viral Vector Production: Supporting the growth of packaging cell lines for adenovirus, lentivirus, and AAV production used in gene therapy.
• Research & Development: Basic cell biology studies, cytotoxicity testing, and process development in laboratory-scale bioreactors and spinner flasks.
• Recombinant Protein Production: Culturing cells engineered to secrete complex therapeutic proteins.

Basic Information

Product Name	Cytodex 3
CAS No.	88895-19-6
Molecular Formula	Not applicable (Microcarrier bead)
Molecular Weight	Not applicable
Synonyms	Dextran Microcarrier; Collagen-coated Dextran Microcarrier; Cytodex® 3; Microcarrier Beads; Cell Culture Microcarriers; Dextran Bead Matrix; Gelatin-coated Microcarrier; Cytodex 3 Microcarriers
EINECS	Contact for details

Quality Control

Our Cytodex 3 is manufactured under strict quality management systems to ensure lot-to-lot consistency critical for bioprocess validation. Each batch is tested for key parameters including bead size distribution, collagen coating integrity, sterility, and endotoxin levels to meet the stringent requirements of cGMP and biopharmaceutical production. Certificates of Analysis (COA) with full release specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the original container is sealed after use to prevent moisture uptake, which can affect performance.

Specification

Item	Specification
Appearance	White, opaque spherical beads
Matrix Material	Cross-linked dextran
Surface Coating	Denatured collagen (Type I)
Bead Diameter	130 - 220 μm
Swelling Factor (in PBS)	Contact for details
Sterility	Sterile (γ-irradiated)
Endotoxin	< 1.0 EU/mL (by LAL test)
Cell Growth Performance	Validated with reference cell lines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.