Description

Amberlite(R) XAD-4 is a non-ionic, macroreticular polymeric adsorbent resin based on a styrene-divinylbenzene copolymer. This high-surface-area resin is engineered for the selective adsorption and purification of organic compounds from aqueous and non-aqueous streams. It is a critical tool for process chemists and engineers in industries requiring high-purity separation, recovery, and decolorization. Key applications span pharmaceutical intermediate purification, wastewater treatment, food and beverage processing, and the isolation of natural products.

Application

• Pharmaceutical Purification: Recovery and purification of antibiotics, steroids, and other active pharmaceutical ingredients (APIs) from fermentation broths or reaction mixtures.
• Wastewater Treatment: Removal of phenolic compounds, pesticides, herbicides, and other hazardous organic pollutants from industrial effluent.
• Food & Beverage Processing: Decolorization of sugar syrups, fruit juices, and edible oils; removal of off-flavors and impurities.
• Natural Product Isolation: Extraction and concentration of flavors, fragrances, vitamins, and other bioactive compounds from plant extracts.
• Chemical Synthesis: Separation of reaction products, catalyst recovery, and purification of organic intermediates.
• Analytical Sample Preparation: Solid-phase extraction (SPE) for pre-concentration of analytes prior to HPLC or GC analysis in environmental and food testing labs.

Basic Information

Product Name	Amberlite(R) XAD-4
CAS No.	37380-42-0
Molecular Formula	(C8H8·C10H10)n
Molecular Weight	N/A (Polymeric resin)
Synonyms	Poly(styrene-co-divinylbenzene); Styrene-divinylbenzene copolymer; XAD-4; Amberlite XAD4; ADSORBENT RESIN XAD-4; Macroreticular adsorbent resin; DVB crosslinked polystyrene resin; Poly(styrene-divinylbenzene) adsorbent
EINECS	253-510-1

Quality Control

Our Amberlite(R) XAD-4 is manufactured under a strict quality management system. Each lot is tested against rigorous internal specifications to ensure consistent performance characteristics such as surface area, pore volume, and particle size distribution. While this product is not of USP/NF or Ph. Eur. grade, it is produced to meet the high standards required for industrial and laboratory separations. A Certificate of Analysis (COA) detailing key physical and chemical parameters is available for every batch upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at ambient temperature (15-25°C). Keep away from strong oxidizing agents. The resin is stable under these conditions for extended periods. Prior to use, the resin may require specific pre-treatment (e.g., washing with solvents) as per the application protocol.

Specification

Item	Specification
Appearance	Opaque white to off-white spherical beads
Matrix	Styrene-divinylbenzene copolymer
Polarity	Non-ionic, hydrophobic
Surface Area (BET)	~725 m²/g (Typical)
Pore Volume	~0.98 mL/g (Typical)
Average Pore Diameter	~50 Å (Typical)
Particle Size Range	20-60 mesh (250-850 µm) (Standard)
Moisture Content	< 1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.