Description

Seprilose is a high-performance chromatography resin widely used for the purification of biomolecules. This product is essential for ensuring the purity, yield, and consistency of sensitive biological products in regulated manufacturing environments. It is a critical material for downstream processing teams in the biopharmaceutical, vaccine, and life sciences research sectors seeking reliable separation solutions.

Application

• Monoclonal Antibody (mAb) Purification: Primary capture and polishing step in antibody manufacturing processes.
• Vaccine Production: Purification of recombinant protein antigens and virus-like particles (VLPs).
• Gene Therapy: Downstream purification of viral vectors such as AAV and lentivirus.
• Enzyme and Protein Purification: Isolation of therapeutic enzymes, growth factors, and other recombinant proteins.
• Oligonucleotide and Plasmid DNA (pDNA) Purification: Used in the purification of nucleic acid-based therapeutics.
• Diagnostic Reagent Manufacturing: Purification of key components for immunoassays and diagnostic kits.
• Process Development & Scale-Up: Employed in R&D and pilot-scale studies to optimize purification protocols.

Basic Information

Product Name	Seprilose
CAS No.	133692-55-4
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Agarose-based Chromatography Media, Cross-linked Agarose Resin, Fast Flow Agarose, Affinity Chromatography Matrix, Bead-based Separation Media, Macroporous Agarose, 6% Cross-linked Agarose, Chromatography Gel Beads
EINECS	Contact for details

Quality Control

Our Seprilose chromatography resin is manufactured under a quality management system and undergoes rigorous testing to ensure batch-to-batch consistency for critical process applications. Each lot is tested for key performance parameters including dynamic binding capacity, flow properties, and ligand density (if functionalized). A comprehensive Certificate of Analysis (COA) documenting purity, physical specifications, and performance data is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. The resin is typically supplied and stored in a 20% ethanol solution to prevent microbial growth; do not allow the resin to dry out. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white spherical beads
Matrix	Cross-linked 6% Agarose
Bead Size Range	45-165 μm
Mean Bead Size	90 μm
Dynamic Binding Capacity (for mAb)	> 40 g/L resin
pH Stability (working range)	2 - 13
Maximum Pressure	0.3 MPa
Flow Rate (recommended)	100 - 500 cm/h

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.