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Epichlorohydrin Activated Cross-Linked*6 % Beaded Ag CAS NO 351377-38-3
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CAS No.:351377-38-3
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
Epichlorohydrin Activated Cross-Linked*6 % Beaded Ag CAS NO 351377-38-3 is a specialized functionalized polymer designed for high-performance affinity chromatography and immobilization applications. Its core value lies in the epichlorohydrin-activated surface, which provides reactive sites for the covalent bonding of ligands, enzymes, or other biomolecules, creating stable, reusable separation media. This product is essential for researchers and process engineers in the biotechnology, pharmaceutical, and diagnostic sectors who require robust, beaded supports for purification, catalysis, or assay development.
Application
- Affinity Chromatography Media: Used as a base matrix for the immobilization of proteins, antibodies, or nucleic acids to create custom purification columns for biomolecules.
- Enzyme Immobilization: Serves as a solid support for covalently binding enzymes, enhancing their stability and reusability in biocatalytic processes and biosensor construction.
- Ligand Coupling for Purification: Ideal for attaching specific chelating agents, dyes, or cofactors to create adsorbents for the selective capture of target compounds from complex mixtures.
- Diagnostic Assay Development: Provides a versatile platform for immobilizing antigens or antibodies in lateral flow assays, ELISA, and other immunoassay formats.
- Solid-Phase Synthesis Support: Can be utilized as a reactive polymer support for the synthesis of peptides, oligonucleotides, or small molecule libraries.
- Process-Scale Biomanufacturing: Employed in the downstream processing of therapeutic proteins, vaccines, and other biologics for large-scale, GMP-compliant purification.
Basic Information
| Product Name | Epichlorohydrin Activated Cross-Linked*6 % Beaded Ag |
| CAS No. | 351377-38-3 |
| Molecular Formula | Contact for details |
| Molecular Weight | Contact for details |
| Synonyms | Epoxy-activated agarose beads; 6% Cross-linked agarose activated with epichlorohydrin; Glycidyl ether-activated Sepharose; Epichlorohydrin-activated beaded agarose; Epoxy-functionalized agarose gel; Activated CH-Sepharose 6B; Agarose, cross-linked, epichlorohydrin-activated; Reactive beaded support for affinity chromatography |
| EINECS | Contact for details |
Quality Control
Our Epichlorohydrin Activated Cross-Linked*6 % Beaded Ag is manufactured under a strict quality management system. Each batch undergoes rigorous testing to ensure consistent performance characteristics such as activation level, bead size distribution, swelling capacity, and ligand binding capacity. Certificates of Analysis (COA) detailing these specifications are provided to guarantee compliance with your research or production requirements.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is moisture-sensitive (hygroscopic); ensure the container is sealed after each use to prevent hydration and maintain reactivity. For long-term storage, consider keeping the material under an inert atmosphere.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white beads |
| Matrix | 6% Cross-linked Agarose |
| Activation Type | Epichlorohydrin (Epoxy) |
| Bead Size Range | 45-165 μm (wet) |
| Swelling Factor | Contact for details |
| Epoxy Group Density | Contact for details |
| Maximum Ligand Binding Capacity | Contact for details |
| Storage Solution | 20% Ethanol |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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