Description

Flestolol Sulfate is a selective β-1 adrenergic receptor antagonist (β-blocker) used in pharmaceutical research and development. This compound is critical for studying cardiovascular pharmacology and developing therapeutic agents for conditions like hypertension and arrhythmias. It is primarily utilized by pharmaceutical companies, contract research organizations (CROs), and academic institutions engaged in preclinical and analytical research.

Application

• Pharmaceutical Reference Standard: Used as a high-purity standard for quality control (QC) and analytical method development in drug manufacturing.
• Cardiovascular Research: Serves as a key pharmacological tool for in vitro and in vivo studies on β-adrenergic receptor function and cardiac physiology.
• Active Pharmaceutical Ingredient (API) Intermediate: Employed in the synthesis and development of β-blocker medications.
• Metabolite Studies: Used in the identification and quantification of drug metabolites during pharmacokinetic and ADME (Absorption, Distribution, Metabolism, Excretion) research.
• Analytical Testing: Applied in HPLC, LC-MS, and other chromatographic techniques for calibration and assay validation.
• Formulation Development: Aids in the development of dosage forms for preclinical evaluation.

Basic Information

Product Name	Flestolol Sulfate
CAS No.	88844-73-9
Molecular Formula	C17H28N2O5 • H2SO4
Molecular Weight	440.49 g/mol
Synonyms	Flestolol hemisulfate; 3-[4-[(1,1-Dimethylethyl)amino]-2-hydroxypropoxy]benzenemethanol sulfate (2:1); (±)-Flestolol sulfate; Flestolol hydrogen sulfate; BTS 49465; L 9394
EINECS	Contact for details

Quality Control

Our Flestolol Sulfate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling via HPLC and other pharmacopeial methods, to ensure it meets the stringent requirements for research and development use. Certificates of Analysis (COA) documenting full specifications are available for every lot.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.