Description

Spherons CAS NO 88529-05-9 is a high-performance, cross-linked polymer bead widely utilized as a versatile chromatographic separation medium. Its uniform particle size and controlled pore structure provide exceptional resolution and reproducibility for demanding analytical and preparative purification processes. This product is essential for industries requiring high-purity separations, including pharmaceutical development, biotechnology, and fine chemical synthesis.

Application

• Size Exclusion Chromatography (SEC/GPC): For the determination of molecular weight distributions of polymers, proteins, and polysaccharides.
• High-Performance Liquid Chromatography (HPLC): As a stationary phase for the purification and analysis of complex biological molecules and synthetic compounds.
• Biomolecule Purification: Isolation and purification of peptides, proteins, antibodies, and nucleic acids in downstream bioprocessing.
• Polymer Analysis: Characterization of synthetic polymers, copolymers, and oligomers to assess purity and structural properties.
• Desalting and Buffer Exchange: Rapid removal of salts, dyes, or other small molecules from biological samples.
• Process-Scale Chromatography: Used in large-scale columns for the industrial purification of active pharmaceutical ingredients (APIs) and valuable intermediates.

Basic Information

Product Name	Spherons
CAS No.	88529-05-9
Molecular Formula	(C3H6O)n • (C2H3N)m
Molecular Weight	Varies by pore size and cross-linking
Synonyms	Spheron; Poly(glycidyl methacrylate-co-ethylene dimethacrylate); GMA-EDMA beads; Polyhydroxy polymer beads; Glycidyl methacrylate-ethyleneglycol dimethacrylate copolymer; Hydrophilic polymer resin; Chromatography media, GMA-based; Macroporous polymer beads
EINECS	Contact for details

Quality Control

Our Spherons are manufactured under a strict quality management system. Each lot is tested to ensure consistent performance characteristics, including particle size distribution, pore volume, and exclusion limits. Certificates of Analysis (COA) detailing lot-specific data are available upon request to support your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, ensure the product is kept in its original packaging to prevent moisture uptake or contamination.

Specification

Item	Specification
Appearance	White to off-white spherical beads
Particle Size	10 µm, 20 µm, or as specified
Pore Size	100 Å, 300 Å, 1000 Å, or as specified
Exclusion Limit	Defined for specified standards (e.g., PEG, Proteins)
Swelling Factor	In water or specified solvent
Functional Groups	Hydroxyl (from epoxy hydrolysis)
pH Stability	2 - 12

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.